半效应浓度(median effect concentration) The molar concentration of an agonist, which produces 50% of the maximum possible response for that agonist. PS:并不仅仅指“致死”,尽管表述在“致死效应“用得最多。
The effects of a stressor or drug generally depend on the exposure time. Therefore, the EC50 (and similar statistics) will be a function of exposure time. The exact shape of this time function will depend upon the stressor (e.g., the specific toxicant), its mechani *** of action, the organi *** exposed, etc. This time dependency hampers the comparison of potency or toxicity between compounds and between different organi *** s.